Targeted alpha therapy (TAT)
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Overview
Targeted alpha therapy (TAT) is an emerging cancer treatment that utilizes alpha-emitting radioisotopes to selectively target and destroy cancer cells while minimizing damage to healthy tissue. This approach involves coupling alpha particle emitters to tumor-seeking molecules like antibodies or peptides. The short-range, high-energy alpha particles deliver a potent dose of radiation directly to cancer cells, leading to their destruction.
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